
The Fascinating History of 7UP®: From Medicinal Tonic to Refreshing Beverage
By Nikki Thrace. Sep 6, 2024
If you grew up enjoying a cold 7UP®, you might be surprised to learn that this beloved lemon-lime soda has an intriguing history that dates back nearly a century. In fact, 7UP’s original formula included an unusual ingredient: lithium citrate, a compound historically used to treat mood disorders.
A Brief History of 7UP
7UP was first introduced to the market in 1929 under the name “Bib-Label Lithiated Lemon-Lime Soda.” It was marketed as a medicinal tonic with a focus on its purported mood-enhancing benefits. The inclusion of lithium citrate was not just a gimmick; during that era, lithium was used to treat various mental health conditions, including depression and bipolar disorder. At the time these sodas were marketed, they were available to the general public. They were sold as beverages with added health benefits, and people could purchase them just like any other soft drink.

What Is Lithium Citrate?
Lithium citrate is a compound of lithium, which was used in small doses to help stabilize mood. In the 1920s, it was believed that a little bit of this compound could have a positive effect on mental well-being. The amount in 7UP was quite minimal, so it wasn’t intended to be a major therapeutic treatment, but rather a subtle addition to the drink’s appeal.
A Shift in Formula
As medical understanding evolved and regulations changed, lithium was removed from 7UP’s formula in 1948. The soda was rebranded simply as 7UP, and its focus shifted from medicinal claims to being a refreshing, caffeine-free beverage.
A Nostalgic Look Back
For those who remember enjoying 7UP in its earlier days, it’s fascinating to see how the drink has evolved. While it no longer offers medicinal benefits, 7UP remains a nostalgic favorite, evoking memories of simpler times, with the same lemon-lime taste.

So next time you pop open a can of 7UP, appreciate its unique history and the journey it has taken from a medicinal tonic to a staple of refreshment. Cheers to that!
References: 7 Up: Originally an Antidepressant | When 7-Up was created in 1929 it contained lithium, a mood-stabilizing drug | The Unknown History of 7 Up
The Topline News team was assisted by generative AI technology in creating this content
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